SARMS are a recent generation of anabolic compounds synthesized to be a superior medicine to anabolic steroids. The objective of SARMs, according to scientists, is to inhibit the estrogenic, androgenic, and cardiovascular side effects which are associated with anabolic steroids.
Uses of SARMs
SARMs have increasingly become popular in the fitness industry as they are considered a safer option than anabolic steroids. SARMs imitate various positive effects of anabolic steroids with minimal cardiovascular, anabolic, and estrogenic side effects via tissue selectivity. The mechanism is, however, not fully developed, and more studies are being conducted to back up the data and draw conclusions. Apart from being the most innovative and newest substance, SARMs are being analyzed as a prospective treatment for various medical conditions, which are listed below.
Muscle Wasting Disorders
Skeletal muscle wasting is common in individuals who are 40 years and above and is considered a life-impacting disorder. According to healthcare reports, human beings lose at least 1% of their body muscle each year, which causes severe impairments in the quality of life. The disorder may appear because of cancer or when the body ages. Androgens are vital substances with the ability to increase muscle mass. They are therefore crucial when dealing with muscle wasting disorder.
Duchene Muscular Dystrophy (DMD)
DMD is a health condition that leads to muscle degeneration due to the genetic mutation of the DMD gene. The condition targets young males and muscle weakness causes patients with DMD to have problems in their lung and heart muscles. If not treated early, it leads to shorter life expectancy due to heart failure. SARMs cycle administered to individuals with DMD theoretically increases protein synthesis and muscle mass levels without off-target side effects.
Recent animal studies show that SARMs are more likely to affect bones and muscles positively. The studies provide a basis for the potential curative effect of SARMs on osteoporosis. However, there are antiresorptive therapies for treating osteoporosis, but using SARMs helps restrain further bone damage.
Alzheimer’s disease occurs when there is Androgen depletion, causing testosterone levels in older males to drop significantly compared to the levels of amyloid protein inside their brains. Hypogonadal men experience decreased cognitive processes such as working memory, episodic memory, executive function, visual-spatial processing, and processing speed. A higher free testosterone index causes visuospatial functioning, improved verbal and visual memory, and visual motor scanning. All the listed functions are controlled by AR-modulated areas of your brain, which makes SARMs effective in treating cognitive disorders caused by hypogonadism. SARMs results have shown the potential to increase the activity of the neprilysin enzyme without causing severe effects on your prostate.
Benefits of Using SARMs
Society accepts SARMs
SARMs, compared to anabolic steroids, are highly regarded and welcomed by many people, especially those from the fitness industry and the bodybuilding community. They have fewer social stigma and taboos attached to them due to their minimal side effects compared to steroids.
Injections Are Not Necessary
SARMs, unlike anabolic steroids, are not administered through injections. You take them orally, and you do not have to worry about using dirty needles, which cause severe infections. You also eliminate the risks associated with unhealthy use of injections which may cause paralysis, blood vessel damage, and muscle injury.
Promotes Fat Loss
SARMs are efficient in assisting the body with losing extra fat. These selective modulators stimulate receptors to break down the fat, which becomes a new energy source. The fat includes the subcutaneous layers, which are located under the skin. SARMs enable the body to develop lean muscles and improve muscle tone and definition, especially for individuals with muscle wasting syndrome.
SARMs are created to mimic the effects of anabolic steroids but with minimal side effects. The primary use of SARMs is promoting lean muscle mass building, but studies are continually done to establish other potential benefits.